Sulbactam for A. baumannii

Height

Age

Serum Creatinine

CrCl (ml/min) by IBW

Body weight

Sex

Male

Female

CrCl (ml/min) by true BW

CrCl (ml/min) by Adjusted BW

Normal Dose
(Full dose)

Sulbactam:

Susceptible: 3-4 g/day

Intermediate resistant 6-8 g/day

Resistant : 9-12 g/day

CrCl
(ml/min)

>30

15-29

<15

Intermittent HD

CRRT

CAPD

Sulperozone
or
Unasyn

3 g q 24 h

1 g q 12 h

3 g q 24 h

2 g q 12 h

3 g q 12 h

2 g q 8 h

3 g q 8 h

3 g q 12 h

3 g q 24 h

Sulbactam for A. baumannii

Normal Dose
(Full dose)

CrCl
(ml/min)

>30

15-29

<15

Intermittent HD

CRRT

CAPD

Sulperozone
or
Unasyn

3 g q 24 h

1 g q 12 h

3 g q 24 h

2 g q 12 h

3 g q 12 h

2 g q 8 h

3 g q 8 h

3 g q 12 h

3 g q 24 h

CrCl
(ml/min)

>30

Intermittent HD

CRRT

CAPD

Sulperazone
or
Unasyn

4 g q 8 h
(+vit K1 10 mg/wk)
3 g q 4 h

15-29

3 g q 12 h

3 g q 8 h

<15

2 g q 12 h

3 g q 12 h

CrCl
(ml/min)

>30

Intermittent HD

CRRT

CAPD

Sulperazone
+
Unasyn

4 g q 8 h
(+vit K1 10 mg/wk)
3 g q 6 h

15-29

3 g q 8 h
(+vit K1 10 mg/wk)
3 g q 6 h

<15

3 g q 12 h

3 g q 8 h

Sulbactam for A. baumannii

Normal Dose (Full dose)

CrCl (ml/min)

>30

15-29

<15

Intermittent HD

CRRT

CAPD

Sulperozone or Unasyn

3 g q 24 h

1 g q 12 h 3 g q 24 h

2 g q 12 h 3 g q 12 h

2 g q 8 h 3 g q 8 h

3 g q 12 h

3 g q 24 h

Normal Dose
(Full dose)

CrCl
(ml/min)

Sulperozone
or
Unasyn

1 g q 12 h

3 g q 24 h

2 g q 12 h

3 g q 12 h

2 g q 8 h

3 g q 8 h